Research Highlights

Yi-Ming Liu

Professor

 liu_sz 1400 J. R. Lynch Street, P.O. Box 17910
Jackson, MS39217-0510

Physical location:
John A. Peoples Science Building
Office: NSB Room #537

Contact:
E-mail: yiming.liu@jsums.edu
Tel: (601) 979-3491
Fax: (601) 979-3674

 

Teaching
Analytical Chemistry CHEM 320
General Chemistry CHEM 141 &142
Spectroscopic Methods CHEM 729


Research Interests:
 Analytical Chemistry: Research in the Liu group is focused on the development of novel analytical methods for sensitive and selective bioassays. A wide range of instrumental techniques including bioluminescence, CE, HPLC, GC-MS/MS, CE-MS/MS, and HPLC-MS/MS are involved. In a particular project funded by National institutes of Health, the group is developing chiral separations based on microchip electrophoresis with mass spectrometric detection. These methods are developed for chiral single cell analysis as applied in metabolic studies of biomedically interesting compounds such as neurotransmitters, environmental toxins, and pharmaceutical chemicals.

 

 

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Selected publications (click here for full list)
  1. X Li, S Zhao, YM Liu, Evaluation of a microchip electrophoresis-mass spectrometry platform deploying a pressure-driven make-up flow, Journal of Chromatography A, 1285, 159-164, 2013.
  2. S Zhao, J Liu, Y Huang, YM Liu, Introducing chemiluminescence resonance energy transfer into immunoassay in a microfluidic format for an improved assay sensitivity, Chem. Commun. 48 (5), 699-701, 2011.
  3. Y Huang, S Zhao, H Liang, ZF Chen, YM Liu, Multiplex detection of endonucleases by using a multicolor gold nanobeacon, Chemistry-A European Journal 17 (26), 7313-7319, 2011.
  4. L.S. Qing, Y. Xue, Y. Zheng, J. Xiong, X. Liao*, L.S. Ding, B.G. Li, Y.M. Liu* “Ligand fishing from Dioscorea nipponica extract using human serum albumin functionalized magnetic nanoparticles,” J. Chromatogr. A 2010, 1217: 4663-4668.
  5. S. Zhao*, Y. Huang, R. Liu, M. Shi, Y. M. Liu* “A Nonenzymatic Chemiluminescent Reaction Enabling Chemiluminescence Resonance Energy Transfer to Quantum Dots,” Chemistry–A European J. 2010, 16: 6142-6145.
  6. Y. Huang, S. Zhao, M. Shi, Y. M. Liu* “Chemiluminescent immunoassay of thyroxine enhanced by microchip electrophoresis,” Anal. Biochem. 2010, 399: 72-77. PMID: 19961826.
  7. S. Zhao, Y. Huang, M. Shi, R. Liu, Y. M. Liu* “Chemiluminescence Resonance Energy Transfer-based Detection for Microchip Electrophoresis,” Anal. Chem. 2010, 82: 2036-2041. PMID: 20121202.
  8. S. Zhao, Y. Huang, Y. M. Liu* “Microchip electrophoresis with chemiluminescence detection for assaying ascorbic acid and amino acids in single cells,” J. Chromatogr. A 2009, 1216: 6746-51.
  9. S. Zhao, Y. Huang, M. Shi, Y. M. Liu* “Quantification of biogenic amines by microchip electrophoresis with chemiluminescence detection,” J. Chromatogr. A 2009, 1216: 5155–59.
  10. S. Zhao, X. Li, Y. M. Liu* “Integrated microfluidic system with chemiluminescence detection for single cell analysis after intracellular labeling,” Anal. Chem. 2009, 81: 3873–78.