CSET Office of Research  
  Jackson State University  
  Box 1800  
  1230 Raymond Road  
  Jackson, MS 39204  
  (601) 979-2024  
 
           
 
   

CSET Center for Environmental Health

    
   
 

 

  
 
 

Paul B. Tchounwou, PhD

Professor and Associate Dean, School of Science and Technology

Center Director
 
 

Center Abstract

  
 
     
  The RCMI-Center for Environmental Health at Jackson State University (JSU) funded by the National Institutes of Health has evolved as a "Center of Excellence" in biomedical research. Since its inception in July 1998, the primary goal of the Center has been to develop and sustain an adequate biomedical research infrastructure, and to provide an excellent opportunity to strengthen biomedical programs at JSU. It has provided a focus and necessary resources to maximize biomedical and health-related research and training, and has significantly contributed to the recent ranking of JSU as a comprehensive, research institution according to Carnegie classification. The Center supports five multi-user core research facilities equipped with state-of-the-art instrumentation for necessary cutting edge research and training in the specific area of biomedical sciences. Between July 1, 2004 and May 31, 2008, all these facilities including the Analytical Core, Moleuclar and Cellular Biology Core, Animal Research Core, Molecular Magnetic Resonance Core, and Biostatistical Support Unit, have continued to be operational. Faculty and students conducting research in these laboratories have published papers in peer-reviewed journals and made presentations at national and international conferences. The number of junior faculty who serve as RCMI investigators has increased substantially due to the successful submission of a supplemental faculty development proposal to NIH/NCRR. Leverage from the RCMI program has also helped in the faculty development by the faculty of other successful extramural proposals. A significant number of both undergraduates and graduate students up to the Ph.D. level have been recruited to participate in the RCMI-supported research. Developmental activities during this period included the organization of workshops on craftsmanship and the tenure and promotion process, and seminars conducted by experts in specific areas of biomedical research.  
     
 
 

Funding Sources

  
 
             
 

Total Funding Amount for FY 07-08:

$1,561,223

 

Projected Funding Amount for FY 08-09:

$1,258,707

 
             
 
 
 

Current Funding

    

Agency Name

Title of Project/Award

  

Amount
 
   
  NIH RCMI-Center for Environmental Health   $1,561,223  
           
 
 

Faculty/Postdoctoral Fellows

  
 
         
  Abdul K. Mohamed      
         
  Paul B. Tchounwou   Molecular Pharmacology and Toxicology  
         
  Hiroyasu Tachikawa   Analytical Chemistry  
         
  Jacqueline J. Stevens   Molecular Biology  
         
  Ibrahim O. Farah   Cancer  
         
  Ken S. Lee   Organic chemistry  
         
  H. Anwar Ahmad   Biostatistics  
         
  Ramzi Kafoury   Lung Biology and Carcinogenesis  
         
  Ernest B. Izevbigie   Cellular Signaling, Phytoceuticals, and Cancer Prevention and Therapies  
         
  Ashton Hamme   Bio-organic chemistry  
         
  Kenneth Ndebele   Immunology and Molecular Biology  
         
  Yaru Song      
         
         
 
 

Publications

  
 
     
 
  • Armstrong, N., Patlolla A and Tchounwou P. Protective effect of ascorbic acid against chromium-induced hepatic and renal toxicity in Sprague Dawley rats. Metal Ions in Biology and Medicine, 10, 636-641, 2008.
  • Brown, E., Yedjou C, and Tchounwou P. Cytotoxicty and oxidative stressin human liver carcinoma cells exposed to arsenic trioxide. Metal Ions in Biology and Medicine, 10, 583-587, 2008.
  • Fortner, A., S. Wang, G. Krishna Darbha, A. Ray, H. Yu and P. Ray. Near Infrared Photo-Induced DNA Damage in the Presence of Copper-dppz Complex: Evidence for the Involvement of Singlet Oxygen, Chem. Phys. Lett., 434, 12, 2007, in print.
  • Fu, P. P., Q. Xia, L. Guo, H. Yu, and P. C. Chan. Toxicity of Kava Kava, J. Environ. Sci. Health, Part C. Environ. Carcinog. & Ecotoxic. Revs., in print, 2008.
  • Izevbigie, Ernest, Carolyn B. Howard, and Ken S. Lee, “V. Amygdalina: Folk Medicine, Analysis, and Potential Application for Cancer Treatment”, Curr. Pharm. Anal., 2008, 4(1), 20-24.
  • Kafoury, R. M., J. M. Hernandez, J. A. Lasky, W.A. Toscano, Jr., and M. Friedman. Activation of transcription factors -B (NF-B) and IL-6 (NF-IL-6) by lipid ozonation products is crucial to interleukin-8 gene expression in human airway epithelial cells, Environmental Toxicology., 22(7): 159-168, 2007.
  • Mohamed, AK, Hardy MG, and Tchounwou PB. Third international symposium on recent advances in environmental health research. International Journal of Environmental Research and Public Health 4(2), 81-83, 2007.
  • Mosely, C. N., L. Wang, S. Gilley, S. Wang, and H. Yu. Light-Induced Cytotoxicity and Genotoxicity of a Sunscreen Agent, 2-Phenylbenzimidazole in Salmonella typhimurium TA 102 and HaCaT Keratinocytes, Int. J. Environ. Res.Public Health, 4(2), 126-131, 2007.
  • Patlolla A, Armstrong N and Tchounwou P. Cytogenetic evaluation of potassium dichromate toxicity in bone marrow cells of Sprague Dawley rats. Metal Ions in Biology and Medicine, 10, 353-358, 2008
  • Patlolla A, Barnes C, Yedjou C, Velma V and Tchounwou P. Oxidative stress, DNA damage and antioxidant enzyme activity induced by hexavalent chromium in Sprague Dawley rats. Environmental Toxicology 22 (In Press) 2008.
  • Ray, P. C., G. K. Darbha, M. R. Nittala, and H. Yu. Miniaturized Gold Nanoparticle-Based Surface Energy Transfer Probe for Sequence Specific HIV-1 Virus DNA Detection, Anal. Chem. accepted, 2008
  • Song, Y. , F. Liang, Y.M. Liu “Quantification of D-amino acids in the central nervous system of Aplysia californica by liquid chromatography/tandem mass spectrometry,” Rapid Comm. Mass Spectr. 2007, 21: 73-77.
  • Song, Y., S. Zhao, P. Tchounwou, Y. M. Liu “A nanoparticle-based solid-phase extraction method for liquid chromatography–electrospray ionization-tandem mass spectrometric analysis,” J. Chromatogr. A, 2007, 1166: 79–84.
  • Steiss, J. E, C. Schaffer, H. A. Ahmad, V. L. Voith. Evaluation of plasma cortisol levels and behavior in dogs wearing bark control collars. Journal Applied Animal Behavior Science, 2007: 106 (1-3), 96-106
  • Stevens, JJ Graham-Evans B, Walker AM, Armstead B and Tchounwou P. Cytotoxic effect of arsenic trioxide in adenocarcinoma colorectal cancer (HT-29) cells. Metal Ions in Biology and Medicine, 10, 458-462, 2008
  • Sutton, D. and PB Tchounwou. Mercury Induces the Externalization of Phosphatidylserine in Human renal proximal tubule (HK-2) cells, Int. J. Environ. Res. and Public Health, 4(2):138-144, 2007
  • Takougang I, Barbazan Ph, Tchounwou P and Noumi E. The value of the freshwater snail dip scoop sampling method in maroinvertebrates bioassessment of sugar mill wastewater pollution in Mbandjock, Cameroon. International Journal of Environmental Research and Public Health 5(1), 68-75, 2008
  • Tchounwou PB and Centeno JA. Toxicologic Pathology. In: Preclinical Development Handbook. Gad SC (ed). John Wiley & Sons. New York. NY. pp 551-580, 2008.
  • Tchounwou, P., Newsome C, Williams J and Glass K. Copper-induced cytotoxicity and transcriptional activation of stress genes in human liver carcinoma cells. Metal Ions in Biology and Medicine, 10, 285-290, 2008.
  • Velma V and Tchounwou, P. Acute toxicity of sodium dichromate to goldfish, Carassium auratus. Metal Ions in Biology and Medicine, 10, 642-646, 2008
  • Walker, AM, Stevens JJ and Tchounwou P. Arsenic trioxide mediated apoptosis in breast (MCF-7) and lung (A549) carcinoma cells. Metal Ions in Biology and Medicine, 10, 135-139, 2008.
  • Wang, Peng., Xiaoke Hu, Sean Cook, , Maria Begonia, Ken Lee, and Huey-Min Hwang, “Effects of Culture Condition on the Production of Ligninolytic Enzymes by White Rot Fungi Phanerochaete chrysosporium (ATCC 20696) and Separation of its Lignin Peroxidase” World J. Microbiol. Biotechnol., in press, 2008.
  • Wang, S., C. Mosley, G. Stewart, H. Yu. Photochemical reaction of a dye precursor 4-chloro-1,2-phenylenediamine and its associated mutagenic effects, J. Photochem. Photobiol. A: Chem., 2008
  • Xu, J.; Hamme, A. T., II. Efficient Access to Isoxazoles from Alkenes Synlett 2008, in press.
  • Yedjou C, Brown E, Rogers C and Tchounwou P. Ascorbic acid modulation of arsenic trioxide toxicity: Implication for the clinical treatment of acute promyelocytic leukemia. Metal Ions in Biology and Medicine, 10, 413-418, 2008.
  • Yedjou C, Haynes L, Dorsey W, McMurray R and Tchounwou P. Lead-induced cytotoxity and oxidative stress in human leukemia (HL-60) cells. Metal Ions in Biology and Medicine, 10, 489-494, 2008.
  • Yedjou C, Rogers C, Brown E and Tchounwou P. Differential effect of ascorbic acid and n-acetyl-cysteine on arsenic trioxide – mediated oxidative stress in human leukemia (HL-60) cells. Journal of Biochemical and Molecular Toxicology 22, 85-92, 2008.
  • Yedjou C, Sutton LM and Tchounwou P. Genotoxic mechanisms of arsenic trioxide effect in human Jurkat T-lymphoma cells. Metal Ions in Biology and Medicine, 10, 495-499, 2008.
  • Yedjou C, Waters D and Tchounwou P. N-acetyl-cysteine protection against lead-induced oxidative stress and genotoxicity in human liver carcinoma cells. Metal Ions in Biology and Medicine, 10, 419-424, 2008.
  • Yedjou GC and Tchounwou PB. In vitro cytotoxic and genotoxic effects of arsenic trioxide on human leukemia cells using the MTT and alkaline single cell gel electrophoresis (comet) assays. Molecular and Cellular Biochemistry, 301, 123-130, 2007.
  • Yedjou GC, and Tchounwou PB. N-acetyl-cysteine affords protection against lead-induced cytotoxicity and oxidative stress in human liver carcinoma (HepG2) cells. International Journal of Environmental Research and Public Health 4(2), 132-137, 2007.
  
 
 

Presentations

  
 
     
 
  • Ahmad, H.A. Broiler Growth Modeling with Neural Network using Simulated Data. Fourth International Symposium on Recent Advances in Environmental Health Research (PB-32), 2007. Marriott Hotel, Jackson, MS, USA. September 16-19.
  • Armstrong N, Patlolla A and Tchounwou P. Protective effect of ascorbic acid against chromium-induced hepatic and renal toxicity in Sprague Dawley rats. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Ayensu, W. K. and P. B. Tchounwou. Mercury Exposure and Effects on the Human Genome Molecular Biology Conference: Cambridge Healthtech, Inc. San Francisco, CA., Feb 27 - March 2, 2007.
  • Ayensu, W. K., R. Isokpehi, I. O. Farah, and E. B. Izevbigie. In Vitro Expression of Glycine Alpha-3, GABA-A -Chloride and -Glutamate- gated Channel Receptors in HepG2 cells upon Exposure to Low Concentrations of Mercury, 98th America Association for Cancer Research (AACR) Conference, April 14-18, 2007.
  • Ayensu, W., I. Farah, R. D. Isokpehi, D. Sarpong, and E. B. Izevbigie. Post–Microarray Analysis of Overexpressed Neurotransmitter Receptors In HepG2 Liver Cells upon Low Level Exposure to Mercury, 4th International Symposium on Recent Advances in Environ. Health Research; Jackson, MS, September 16-19, 2007.
  • Brown E, Yedjou C, and Tchounwou P. Cytotoxicty and oxidative stress in human liver carcinoma cells exposed to arsenic trioxide. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Brown E, Yedjou CG and Tchounwou PB. Genotoxic Effects and Oxidative Stress in Human Liver Carcinoma (HepG2) Cells Exposed to Arsenic Trioxide. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Brown E, Yedjou CG and Tchounwou PB. Molecular basis for arsenic-induced oxidative stress and genotoxic in human liver carcinoma (HepG2) cells. Paper presented at the Annual Meeting of the American Association for Cancer Research, San Diego, CA. April 12 -16, 2008.
  • Carpenter S, Brown E, Yedjou CG and Tchounwou PB. Estradiol Enhances Cellular Proliferation in Human Jurkat T-Cells and Human Leukemia (Hl-60) Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Davis, A., R. Isokpehi, T. Torok, B. Graham-Evans, and N. Campbell. Differential DNA damage from ionizing radiation in two strains of A. pullulans 4th International Symposium on Advances in Environ. Health, Jackson, MS, USA, September 16-19, 2007.
  • Glass K and Tchounwou P. Cytotoxicity, oxidative stress and genotoxicity in human liver carcinoma cells exposed to dinitrotoluenes. Paper presented at the 47th Annual Meeting of the Society of Toxicology. Washington State Convention and Trade Center. Seattle, Washington. March 16-20, 2008.
  • Glass, Konsuela and Tchounwou PB. Apoptosis in Human Liver Carcinoma (HepG2) Cells Exposed to Dinitrotoluenes. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Gompa N, Wilson T, Njoku A, Reddy R and Tchounwou PB. Environmental Meteorology and Climatology. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Gresham, L. and E. Izevbigie. Isolation and restriction enzyme digestion of high molecular weight-genomic DNA from V. Amygdalina, 4th International Symposium on Advances in Environ. Health, Jackson, MS, USA, September 16-19, 2007.
  • Hamme, Ashton. “One Pot Synthesis of Spiro(indoline-2,5′-isoxazolines) and Spiro(indoline-2,5′-pyrazolines) via 1,3-Dipolar Cycloaddition” (Invited Lecture) 235th American Chemical Society National Meeting, New Orleans, LA, April 10, 2008
  • Hamme, Ashton. “The Application and Development of the 1,3-Dipolar Cycloaddition Reaction Towards Potential Biologically Active Compounds” (Invited Lecture) Florida A&M University, Department of Pharmacy, Tallahassee, FL, November 7, 2007.
  • Hamme, Ashton. “Theoretical and Experimental Studies towards the Synthesis of Potential Estrogen Mimics” Fourth International Symposium on Recent Advances in Environmental Health Research, Jackson, MS, September 16-19, 2007.
  • Hannah S, Haile S, Sutton D, Yedjou CG and Tchounwou PB. Lead-Induced Cytotoxicity and Oxidative Stress in Human Breast Carcinoma (MCF-7) Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Isokpehi RD, Tchounwou PB, Graham-Evans B and Cohly HHP. Extracting Gene-Arsenic Interaction from High-Dimensional Datasets. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Izevbgie E, Yedjou C, Ayuri D, and Tchounwou PB. In-Vitro Cytotoxic and Genotoxic Effects of Vernonia amygdalina Extracts on Human Breast (MCF-7) Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Izevbigie, Ernest. American Association for Cancer Research, CA
  • Izevbigie, Ernest. ASPAD Conference in Washington DC
  • Izevbigie, Ernest. Fourth International Symposium on Recent Advance on Environmental Health Research, September 16-19, 2007
  • Kafoury RM and Tchounwou PB. Diesel Exhaust Particles Induce Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Gene Expression in Human Airway Epithelial Cells (A 549). Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Kafoury, R. M. (2007). Pro-Inflammatory Cytokine Profiling in Determining Environmentally-Induced Lung Disease: Exacerbation of Asthma or Chronic Obstructive Pulmonary Disease (COPD). Fourth International Symposium on Advances in Environmental Health Research, September 19-22, Marriott Hotel, Jackson, Mississippi, USA.
  • Kelly J, Tchounwou PB and Kafoury R. Inhibition of Exracellularly-Regulated Kinase (ERK) Downregulates Apoptosis Induced by Diesel Exhaust Particles-Bound Polycyclic Aromatic Hydrocarbons (PAHs) in Alveolar Macrophages. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Kishinhi SS, Tchounwou PB, Farah IO, Woodrey M, Rupel D and Sims M. Assessment of Bacteriological Water Quality in Two Bayous of Grand Bay Nerr Mississippi. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Ladner DC and Tchounwou PB. Growth and Photosynthesis of Tomato, Lycopersicon esculenum, in Response to Biological Chitin Amendment. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Ladner DC, Tchounwou PB and Lawrence GW. Evaluation of Ecologic on the Root Knot Nematode, Meloidogyne incognita, and Tomato, Lycopersicon esculenum. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Lee, Ken S., “RENEWABLE ENERGY: Future Energy System”, KSEA-MS Branch Fall Seminar, Jackson, MS, Nov. 2007.
  • Lee, Ken S., Maria Begonia, and Huey-Min Hwang, “Extraction and Hydrolysis of Cellulosic Materials from Sawdust: Pretreatment of Sawdust”, 2nd International Peace Conference and Symposium: Peace Through Understanding, Jackson, MS, April, 2008.
  • Lee, Ken S., T. Demeritte, J. Thorn, M. Begonia, and H. Hwang, “Application of ionic liquid in separation of cellulosic material from lignin in sawdust”, 11th Annual Green Chemistry and Engineering Conference, Washington D.C., June, 2007.
  • Lee, Ken S., Teresa Demeritte, Jeffrey Thorn, Maria Begonia, and Huey-Min Hwang, “Application of ionic liquid in separation of cellulosic material from lignin in sawdust”, UKC2007, Korean Scientists and Engineers Assoiciation, Washington D.C., Aug., 2007.
  • Magee-Wood NR and Tchounwou PB. Patterns of Abundance and Distribution, and their Relation to Environmental Factors, in Groundfish of the Northern Gulf of Mexico. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Moore P, Ishaque A, Patlolla A, Yedjou CG and Tchounwou PB. Malathion-Induced Transcriptional Activation of Stress Genes in Human Liver Carcinoma (HepG2) Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Mosely, C., D. Brown, I. Wicks, A. Odges, S. Wang and H. Yu, Light-induced DNA cleavage by hair dye ingredient chemicals: chlorine substituted or non-substituted phenylenediamines, 4th International Symposium on Advances in Environ. Health, Jackson, MS, USA, September 16-19, 2007.
  • Ndebele K, McMurray R, Graham B and Tchounwou PB. Study and Characterization of Xenoestrogen Effects on T-Cell Mediated Immunity. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Newsome CR and Tchounwou PB. Copper-Induced Apoptosis in Human Liver Carcinoma (HepG2) Cells using Annexin V and Caspase-3. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Patlolla A, Armstrong N and Tchounwou P. Cytogenetic evaluation of potassium dichromate toxicity in bone marrow cells of Sprague Dawley rats. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Patlolla A, Barnes C, Yedjou C, Velma V and Tchounwou P, Patlolla A, Centeno A and Todorov T. Arsenic-induced biochemical and genotoxic effects, and speciation in tissues of Sprague-Dawley rats. Paper presented at the 4th International Conference on Trace Element Speciation in Biomedical, Nutritional and Environmental Sciences. Munich, Germany. May 25-29, 2008.
  • Patlolla A, Barnes C, Yedjou C, Velma V and Tchounwou P. Oxidative stress, DNA damage and antioxidant enzyme activity induced by hexavalent chromium in Sprague Dawley rats. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Patlolla AK and Tchounwou PB. Multiwalled Carbon Nanotube-Induced Cytotoxicity, Genotoxicity and Apoptosis in Normal Human Dermal Fibroblast Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Patlolla AK, and Tchounwou PB. Multiwalled carbon nanotube induces cytotoxicity, genotoxicity and apoptosis in normal human fibroblast cells. 38th Annual Meeting of Environmental Mutagen Society, Atlanta, GA. October 20-24, 2007.
  • Patlolla AK, Knighten B and Tchounwou PB. Serum Alkaline and Acid Phosphatases as Biomarkers of Carbon Nano-Tube Induced Hepatotoxicity in Male Swiss-Webster Mice. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Patlolla AK, Knighten B, McAlister D and Tchounwou P. Study of hepatotoxicity biomarkers in Swiss-Webster mice with carbon nanotubes. Paper presented at the 47th Annual Meeting of the Society of Toxicology. Washington State Convention and Trade Center. Seattle, Washington. March 16-20, 2008.
  • Patlolla AK, McAllister D and Tchounwou PB. Serum lactate dehydrogenase [LDH] and Bilirubin [direct] as biomarkers of arsenic trioxide induced hepatotoxicity in Sprague-Dawley rats. 72nd Annual Meeting of the Mississippi Academy of Science. Olive Branch, MS. February 20-22, 2008.
  • Patlolla AK, Moore P and Tchounwou PB. Cytogenetic Evaluation of Malathion Toxicity in Sprague-Dawley Rats. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Patlolla AK, Moore P and Tchounwou PB. DNA damaging effect of malathion in peripheral blood leucocytes of Sprague-Dawley rats. Paper presented at the Annual Meeting of the American Association for Cancer Research, San Diego, CA. April 12 -16, 2008.
  • Pavereddy R and Tchounwou PB. Chromium-Induced Oxidative Stress in Goldfish, Carassius auratu. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Powell, A. and B. Graham-Evans, Molecular and Cellular Effects of Mercury on human Jurkat T-cells, 4th International Symposium on Advances in Environ. Health, Jackson, MS, USA, September 16-19, 2007.
  • Reddy RS, Chigbu P and Tchounwou PB. Environmental Modeling and Prediction for Climate and Seasonal Fluctuations over The Grand Bay Area. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Reese, T. and B. Graham-Evans, Molecular and Cellular Effects of Lead on Human Epithelial cells, (HaCaT), 4th International Symposium on Advances in Environ. Health, Jackson, MS, USA, September 16-19, 2007
  • S. Wang, E. Booker, Y. Liu and H. Yu, Cytotoxicity of FE3O4 nanoparticles to human skin HaCat Keratinocytes, 4th International Symposium on Advances in Environ. Health, Jackson, MS, USA, September 16-19, 2007.
  • Sama MT, Mbanya D, and Tchounwou PB. The Epidemiology of HIV/AIDS in Cameroon: Implication for Control. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Song Y, Tchounwou PB and Liu Y. HPLC-MS/MS Determination of Trace Triazine Pesticides in Surface Water using Superparamagnetic FE3O4 Nanoparticles for Sample Extraction. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Stevens JJ, Graham-Evans B, Walker AM, Armstead B and Tchounwou P. Cytotoxic effect of arsenic trioxide in adenocarcinoma colorectal cancer (HT-29) cells. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Stevens JJ, Walker AM, and Tchounwou PB. Arsenic Induces Cytotoxicity and Apoptosis in Adenocarcinoma Colorectal Cancer (Ht-29) Cells through Oxidative Stress. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Steverson M, Yedjou CG and Tchounwou PB. Lead-Induced Oxidative Stress in Human Liver Carcinoma (HepG2) Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Steverson, M., C. Yedjou, and P.B. Tchounwou, Lead-induced oxidative stress in human liver carcinoma (HepG2) cells, 4th International Symposium on Advances in Environ. Health, Jackson, MS, USA, September 16-19, 2007.
  • Sutton L, Yedjou C, Campbell N and Tchounwou PB. In-Vitro Cytotoxic and Genotoxic Effect of Arsenic Trioxide on Human Jurkat T- Cells using the MTT and Alkaline Single Cell Electrophoresis (Comet) Assays. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Takougang I, Barbazan P, Tchounwou PB and Noumi E. The Value of the Freshwater Snail Dip Scoop Sampling Method in Macroinvertebrates Bioassessment of Sugar Mill Wastewater Pollution in Mbandjock, Cameroon. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Tchounwou P, Newsome C, Williams J and Glass K. Copper-induced cytotoxicity and transcriptional activation of stress genes in human liver carcinoma cells. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Tchounwou P. Biomarkers of carcinogenesis and genetic susceptibility. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Tchounwou PB, Patlolla AK and Centeno JA. Arsenic-Induced Biochemical and genotoxic effects in Sprague-Dawley rats. Paper presented at the 11th International Congress of Toxicology. Montreal, Canada. July 15-19, 2007.
  • Thomas, M. S., Y. Chen, X. Zhang, L. R. Lockridge, H. Wang, and S. I.N. Ekunwe. Organic Solvent Fractions of Ocimum gratissimum Leaves Exhibit Greater Anti-Proliferative Activity on Prostate Adenocarcinoma (PC-3) Cells than its Aqueous Crude Extract, 4th International Symposium on Recent Advances in Environ. Research, Jackson, MS, September 16-19, 2007.
  • Velma V and Tchounwou P. Acute toxicity of sodium dichromate to goldfish, Carassium auratus. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Walker AM, Stevens JJ and Tchounwou P. Arsenic trioxide mediated apoptosis in breast (MCF-7) and lung (A549) carcinoma cells. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Walker AM, Stevens, JJ and Tchounwou PB. P53 And Bcl-2 Expression and DNA Synthesis in Breast and Lung Carcinoma Cells Exposed to Arsenic Trioxide. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Waters D, Yedjou CG and Tchounwou PB. N-Acetyl-L-Cysteine (NAC) Inhibits Oxidative Stress and Genotoxicity in Lead Nitrate-Treated HepG2 Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Watkins J, Chigbu P, Tchounwou PB, Farah I and Sims M. Assessment of the Macrobenthic Invertebrate Abundance and Distribution in Three Mississippi Gulf Coast Bayous. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Wenzel, Bruce and Ken Lee, “Research on Biodiesel Fuel Produced from Wasted Vegetable Oil”, 2nd International Peace Conference and Symposium: Peace Through Understanding, Jackson, MS, April 2008.
  • Yedjou C and Tchounwou P. Lead induces apoptosis in human leukemia cells via oxidative stress. Paper presented at the 47th Annual Meeting of the Society of Toxicology. Washington State Convention and Trade Center. Seattle, Washington. March 16-20, 2008.
  • Yedjou C, Brown E, Rogers C and Tchounwou P. Ascorbic acid modulation of arsenic trioxide toxicity: Implication for the clinical treatment of acute promyelocytic leukemia. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Yedjou C, Haynes L, Dorsey W, McMurray R and Tchounwou P. Lead-induced cytotoxity and oxidative stress in human leukemia (HL-60) cells. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Yedjou C, Rogers C, Brown E and Tchounwou P. Differential effect of ascorbic acid and n-acetyl-cysteine on arsenic trioxide – mediated oxidative stress in human leukemia (HL-60) cells. Paper presented at the Annual Meeting of the American Association for Cancer Research, San Diego, CA. April 12 -16, 2008.
  • Yedjou C, Sutton LM and Tchounwou P. Genotoxic mechanisms of arsenic trioxide effect in human Jurkat T-lymphoma cells. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Yedjou C, Waters D and Tchounwou P. N-acetyl-cysteine protection against lead-induced oxidative stress and genotoxicity in human liver carcinoma cells. Paper presented at the 10th International Symposium on Metal Ions in Biology and Medicine. Corsica, France. May 18-23, 2008.
  • Yedjou CG and Tchounwou PB. Arsenic Trioxide-Induced Apoptosis in Human Leukemia (Hl-60) Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Yedjou CG and Tchounwou PB. Ascorbic Acid and Arsenic Trioxide as Potent Modulators of Oxidative Stress and Morphological Changes Characteristics of Apoptosis in Human Leukemia (Hl-60) Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Yedjou CG and Tchounwou PB. Ascorbic Acid and Arsenic Trioxide as Potent Modulators of Oxidative Stress and Morphological Changes Characteristics of Apoptosis in Human Leukemia (Hl-60) Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Yedjou CG, Dorsey W, Tchounwou PB and McMurray R. Lead-Induced Cytotoxicity and Oxidative Stress in Human Leukemia (Hl-60) Cells. Paper presented at the Fourth International Symposium on Recent Advances in Environmental Health Research. Marriott Hotel, Jackson, Mississippi. September 16-19, 2007.
  • Zarif, Jelani C. and Stephen I.N. Ekunwe, Human Prostate Cancer Cells (PC-3) Show Increased Sensitivity to Treatment with Heated Leaf Extracts of Ocimum gratissimum, 3rd Annual National Symposium on Prostate Cancer, March 19-20, 2007, Clark Atlanta University in Atlanta, GA.
  • Zhang, Y., C. Howard, and E. Izevbigie. Vernonia amygdalina extracts may decrease paclitaxel, doxorubixine, and vincristine therapeutic dosage, 4th International Symposium on Advances in Environ. Health, Jackson, MS, USA, September 16-19, 2007.
  
 
 

Contact Information

  
 
     
  Dr. Paul B. Tchounwou, Deputy Program Director  
     
  RCMI-Center for Environmental Health  
  Jackson State University  
  Faculty Apartment #22  
  1400 J. R. Lynch Street  
  Jackson, MS 39217  
     
  Phone: 601.979.3448   Fax: 601.979.1863  
     
   paul.b.tchounwou@jsums.edu  
     
 

Web Link: www.jsums.edu/cset