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Stephen I. N. Ekunwe, Ph.D.

Room # 442, John A. Peoples Science Building
Title Assistant Chair & Associate Professor of Biology

OFFICE HOURS 

MON & THURS:  8.00 AM    to 12.00 NOON

      or by appointment
PHONE  601-979-3476
FAX 601-979-5853
Email stephen.i.ekunwe@ccaix.jsum.edu

 

EDUCATION

 
1985  

Jackson State University, Jackson, Mississippi, B.Sc (Biology)
1990 Jackson State University, Jackson, Mississippi, M.Sc (Biology)
1998 Michigan State University, E. Lansing, Michigan, Ph.D. (Molecular Biology)
1998 Michigan State University, E. Lansing, Michigan, Certificate. (Molecular Laboratory Diagnostics)

             

RESEARCH FOCUS AND INTERESTS

  • Medicinal plant products and their effects on colorectal cancer cells and wound healing
  • Isolation and characterization of potential degraders of polycyclic aromatic hydrocarbons (PAHs) and their possible use in bioremediation applications
  • Interaction between bacteriophage T4 and its host, Escherichia coli K-12

Ongoing Research Support

HBCUs BEAT Cancer Program                               Ekunwe (PI)        10/1/05 - 9/29/06

NAFEO CANCER RESEARCH CONSORTIUM

Potential Anti-colon Cancer Agents in whole Leaf Extracts of Eb'amwonkho, (Nigerian Basil)

 

Publications
 

Yi Zhang, Huey-Min Hwang*, and Stephen Ekunwe. "Comparing cytotoxicity and genotoxicity in HaCat cels caused by 6-aminochrysene and 5,6-chrysenequinone under UVA irradiation". Environmental Toxicology and Chemistry. In Press, 2005.

 

Stephen I. N. Ekunwe, Rochelle D. Hunter and Huey-Min Hwang. Ultraviolet Radiation Increases the Toxicity of Pyrene, 1-Aminopyrene and 1-Hydroxypyrene to Human Keratinocytes.  Int. J. Environ. Res. Public Health, 2005, 2(1): 58-62.

 

Rochelle D. Hunter, Stephen I. N. Ekunwe, Daniel E. Dodor, Huey-Min Hwang and Lynette Ekunwe.  Bacillus subtilis is a Potential Degrader of Pyrene and Benzo[a]pyrene.   Int. J. Environ. Res. Public Health, 2005, 2(2): 267-271.

 

Daniel E. Dodor, Huey-Min Hwang and Stephen I. N. Ekunwe.    Oxidation of Anthracene and Benzo[a]pyrene by Immobilized Laccase from Trametes versicolor. Enz Microb Technol, 2004, 35: 210-217.

 

Zheng, Baoying, Huey-Min Hwang, Hongtao Yu, and Stephen Ekunwe. DNA Damage Produced in HaCaT Cells by Combined Fluoranthene Exposure and Ultraviolet A Irradiation. Environ Mol Mut, 2004, 44: 151-155.

 

Izevbigie EB, Ekunwe SI, Jordan J, and Howard CB.  Ethanol Modulates the Growth of Human Breast Cancer Cells in vitro. Exp Biol Med, 2002, 227(4): 260-5.

 

Ekunwe, SIN. Role of HEXXH motif of zinc metalloproteases in activity of Escherichia coli e14 encoded Lit protein.  Metal Ions in Biol. Med. 2000, 6: 704-706.

 

Bingham, R., Stephen I. N. Ekunwe, Sherry Falk, Larry Snyder, and Colin Kleanthous. The Major Head Protein of Bacteriophage T4 Binds Specifically to Elongation Factor Tu.  J. Biol. Chem. 2000, 275(30): 23219- 23226.

Georgiou, T., Y-T.N. Yu, S. Ekunwe, M.J. Buttner, A-M. Zuurmond, B. Kraal, C. Kleanthous and L. Snyder. Specific peptide-activated proteolytic cleavage of Escherichia coli elongation factor, Tu.  Proc. Natl. Acad. Sci. USA, 1998, 95: 2891-2895.