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Ashton T. Hamme, III, Ph.D.
Assistant Professor
601-979-3713
ahamme@ccaix.jsums.edu
 


Education:

B.S, in Chemistry from Jackson State University, 1992
Ph.D. in Organic Chemistry from The Ohio State University, 1998

Research Interests:

Synthetic Organic Chemistry

Publications:

Hamme, A.T.; Paquette, L.A “Asymmetric Conjugate Additions of Chiral Allyl- and Crotylphosphamide Anions to -unsaturated carbonyl compounds”. Chemtracts-Organic Chemistry 1994, 7, 24.

Webb, T. E.; Pham-Nguyen, M.-H.; Darby, M.; Hamme, A. T. “Pharmacokinetics Relevant to the Anti Carcinogenic and Anti-tumor Activities of Glucarate and the Synergistic Combination of Glucarate: Retinoid in the Rat” Biochemical Pharmacology 1994, 47, 1655.

Paquette, L. A.; Hamme, A. T.; Kuo, L. H.; Doyon, J.; Kruezholz, R. “Probe of the Stereochemically Determining Step in Squarate Ester Cascade. Proof that Helical Equilibration with the Octatetraene Intermediate is Responsible, and Definition of Steric Control Elements” J. Am. Chem. Soc. 1997, 119, 1242.

Paquette, L. A.; Kuo, L. H.; Hamme, A. T.; Kruezholz, R.; Doyon, J. “Sensitivity of Substitution to the Extent of Self-Immolative Chirality Transfer during Reaction Cascades Originating from Squarate Esters” J. Org. Chem. 1997, 62, 1730.

South, M. S.; Zeng, Q.; Rueppel, M. L.; Hamme, A.T. “Substituted Polycyclic Aryl and Heteroayl Pyridones Useful for Selective Inhibition of the Coagulation Cascade,” WO 0187842.

South, M. S.; Hamme, A. T.; Neumann, W. L.; Jones, D. E.; Ruppel, M. L “Substituted Polycylic Aryl and Heteroaryl Pyrimidinones Useful for Selective Inhibition of the Coagulation Cascade,” WO 0187851.

Sikorski, J. A.; Durley, R. C.; Mischke, D. A.; Reinhard, E. J.; Fobian, Y. M.; Tollefson, M. B.; Wang, L.; Grapperhaus, M. L.; Hickory, B. S.; Massa, M. A.; Norton, M. B.; Vernier, W. F.; Parnas, B. L.; Promo, M. A.; Hamme, A. T.; Spangler, D. P.; Rueppel, M. L. “Use of Substituted N,N’Disubstituted Non-Fused Heterocyclo Amino Compounds For Inhibiting Cholesteryl Ester Transfer Protein Activity,” US 6451830 B1.

Sikorski, J. A.; Durley, R. C.; Mischke, D. A.; Reinhard, E. J.; Fobian, Y. M.; Tollefson, M. B.; Wang, L.; Grapperhaus, M. L.; Hickory, B. S.; Massa, M. A.; Norton, M. B.; Vernier, W. F.; Parnas, B. L.; Promo, M. A.; Hamme, A. T.; Spangler, D. P.; Rueppel, M. L. “Use of Substituted N,N-Disubstituted Fused-Heterocyclo Amino Compounds for Inhibiting Cholesteryl Ester Transfer Protein Activity,” US6455519 B1.

Sikorski, J. A.; Durley, R. C.; Mischke, D. A.; Reinhard, E. J.; Fobian, Y. M.; Tollefson, M. B.; Wang, L.; Grapperhaus, M. L.; Hickory, B. S.; Massa, M. A.; Norton, M. B.; Vernier, W. F.; Parnas, B. L.; Promo, M. A.; Hamme, A. T.; Spangler, D. P.; Rueppel, M. L. “Substituted N-Phenyl,N-Heteroaralkyl Aminoalcohol Compounds for Inhibiting Cholesteryl Ester Tranfer Protein Activity,” US 6458803 B1.