{"id":972,"date":"2013-05-15T16:18:11","date_gmt":"2013-05-15T16:18:11","guid":{"rendered":"https:\/\/www.jsums.edu\/chemistry\/?page_id=972"},"modified":"2013-05-15T16:18:43","modified_gmt":"2013-05-15T16:18:43","slug":"naomi-flowers-campbell","status":"publish","type":"page","link":"https:\/\/www.jsums.edu\/chemistry\/naomi-flowers-campbell\/","title":{"rendered":"Naomi Flowers Campbell"},"content":{"rendered":"\n\n\n\n\n\n\n\n
\n

Associate Professor <\/b><\/i><\/strong><\/h4>\n<\/td>\n<\/tr>\n

\u00a0\"Campbell\"<\/a><\/td>\n1400 J. R. Lynch Street, P.O. Box 17910
\nJackson, MS39217-0510 <\/p>\n

Physical location:
\n<\/i><\/b><\/span>John A. Peoples Science Building
\nOffice: room #504<\/p>\n

Contact:
\n<\/i><\/b><\/span>E-mail: Naomi.f.campbell@jsums.edu
\nTel: (601) 979-3489
\nFax: (601) 979-3674<\/p>\n

 <\/td>\n<\/tr>\n

\n

Teaching<\/b><\/span><\/h4>\n<\/td>\n<\/tr>\n

Introduction to Chemistry CHEM 131
\nGeneral Chemistry I CHEM 141
\nForensic Chemistry CHEM 371
\nForensic Chemistry Laboratory CHML 371
\nBiochemistry I\u00a0 CHEM 431\/531
\nBiochemistry Laboratory CHML 431\/531
\nForensic Practicum CHEM 475
\nAdvanced Biochemistry I\u00a0 CHEM 731
\nBiochemistry II CHEM 432\/532
\nAdvanced Molecular Biology CHEM 733<\/td>\n<\/tr>\n
 <\/p>\n

Research Interests<\/b><\/span><\/h4>\n<\/td>\n<\/tr>\n

Biochemistry<\/i><\/span>
\nResearch in the Campbell group focuses on environmental genomics.\u00a0 The long-term goal of the research is to elucidate the mechanism of low-dose ionizing radiation, ultraviolet radiation, and oxidative damage on induced transgeneration genomic instability and DNA methylation.\u00a0 Ionizing radiation and oxidative damage can interfere with the normal functional of the DNA methylation machinery, which may lead to a change in the DNA and\/or chromatin remodeling, and changes in transcription activity.\u00a0 The methylation of cytosine bases is a natural modification of DNA that does not involve a change in DNA sequence, can affect the remodeling of chromatin, and the level of transcription in a cell.\u00a0 Chromatin structure plays a major role in the control of gene expression because DNA packaged into chromatin is less accessible to the transcription machinery.\u00a0\u00a0 The relaxing of the chromatin structure is necessary for gene expression because the tightly compacted chromatin structure shield a vast number of potential binding sites for transcription activators in eukaryotic cells.\u00a0 Enhancers and co-activators modulate transcription activity by disrupting the local chromatin structure to expose additional regions to the transcription machinery.\u00a0 The methyl group of 5-methylcytosine protrudes into the major groove of the DNA double helix and can interfere with binding of proteins that stimulate transcription.\u00a0 Most genes are located in the CpG islands regions of the genome and the gene sequences contain approximately four-fold as many CpG sequences as the remainder of the genome.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Associate Professor \u00a0 1400 J. R. Lynch Street, P.O. Box 17910 Jackson, MS39217-0510  Physical location: John A. Peoples Science Building Office: room #504 Contact: E-mail: Naomi.f.campbell@jsums.edu Tel: (601) 979-3489 Fax: (601) 979-3674   Teaching Introduction to Chemistry CHEM 131 General Chemistry I CHEM 141 Forensic Chemistry CHEM 371 Forensic Chemistry Laboratory CHML 371 Biochemistry I\u00a0 […]<\/p>\n","protected":false},"author":32,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.jsums.edu\/chemistry\/wp-json\/wp\/v2\/pages\/972"}],"collection":[{"href":"https:\/\/www.jsums.edu\/chemistry\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.jsums.edu\/chemistry\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.jsums.edu\/chemistry\/wp-json\/wp\/v2\/users\/32"}],"replies":[{"embeddable":true,"href":"https:\/\/www.jsums.edu\/chemistry\/wp-json\/wp\/v2\/comments?post=972"}],"version-history":[{"count":2,"href":"https:\/\/www.jsums.edu\/chemistry\/wp-json\/wp\/v2\/pages\/972\/revisions"}],"predecessor-version":[{"id":974,"href":"https:\/\/www.jsums.edu\/chemistry\/wp-json\/wp\/v2\/pages\/972\/revisions\/974"}],"wp:attachment":[{"href":"https:\/\/www.jsums.edu\/chemistry\/wp-json\/wp\/v2\/media?parent=972"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}