Ifedayo Victor Ogungbe

 Assistant Professor

 Victor 1400 J. R. Lynch Street, P.O. Box 17910
Jackson, MS39217-0510

Physical location:
John A. Peoples Science Building
Office: Room #528B

Contact:
E-mail: ifedayo.v.ogungbe@jsums.edu
Tel: (601) 979-3719
Fax: (601) 979-3674

Teaching

Qualitative Organic Analysis, Physical Organic Chemistry


Research Interests: 

Characterization and biological activity of small molecules, Molecular recognition and interactions, Bioinspired design. We use computational chemistry, structural biology, organic synthesis, as well as biochemical (in vitro and in vivo) tools and assays to study how bioactive compounds and/or their mimetic interact with molecular targets.  We hope that the knowledge generated from our work will help in the development of new therapies and materials.


Selected publications (Click here for full list)

  1. Setzer WN and Ogungbe IV. In-silico investigation of antitrypanosomal phytochemicals from Nigerian medicinal plants. PLoS Negl Trop Dis  2012, 6(7): e1727.
  2. Ogungbe IV, Singh M, and Setzer WN. Antileishmanial natural products from plants. Studies in Natural Products Chemistry 2012, 36, 331-377.
  3. Schmidt TJ, Alves TMA, Biavatti MW, Brun R, Da Costa FB, Ferreira VF, Khalid SA, de Lacerda MVG, Lago JHG, Leon LL, de Castro SL, Lopes NP, das Neves Amorim RC, Niehues M, Ogungbe IV, Pohlit AM, Romanha AJ,  Scotti MT, Setzer WN,  Soeiro MdC, Steindel M, Tempone AG. The potential of secondary metabolites from plants as drugs/leads against protozoan neglected diseases – Part II. Current Medicinal Chemistry 2012, 19, 2176-2228.
  4. Schmidt TJ, Alves TMA, Biavatti MW, Brun R, Da Costa FB, Ferreira VF, Khalid SA, de Lacerda MVG, Lago JHG, Leon LL, de Castro SL, Lopes NP, das Neves Amorim RC, Niehues M, Ogungbe IV, Pohlit AM, Romanha AJ,  Scotti MT, Setzer WN,  Soeiro MdC, Steindel M, Tempone AG. The potential of secondary metabolites from plants as drugs/leads against protozoan neglected diseases – Part I. Current Medicinal Chemistry 2012, 19, 2128-2175.
  5. Ogungbe IV, Hill GM, Crouch RA, Vogler B, Singh M, Haber WA, and Setzer WN. Prenylated Isoflavonoids from Rhynchosia edulis. Nat. Prod. Comm. 2011, 6, 1637-1644.
  6. Harris SM, McFeeters H, Ogungbe IV, Cruz-Vera LR, Setzer WN, Jackes BR, and McFeeters RL. Peptidyl-tRNA hydrolase screening combined with molecular docking reveals the antibiotic potential of Syzygium johnsonii bark extract. Nat. Prod. Comm. 2011, 6, 1421-1424.
  7. Helms KM, Wilson RC, Ogungbe IV, Setzer WN, and Twigg PD. Vitexin Inhibits Polyubiquitin Synthesis by the Ubiquitin-conjugating Enzyme E2-25K. Nat. Prod. Comm. 2011, 6, 1411-1416.
  8. Ogungbe IV, Crouch RA, Haber WA, and Setzer WN. Phytochemical Investigation of Verbesina turbacensis Kunth: Trypanosome Cysteine Protease Inhibition by (–)-Bornyl Esters. Nat. Prod. Comm. 2010, 5, 1161–1166.
  9. Ogungbe IV and Setzer WN. Comparative Molecular Docking of Antitrypanosomal Natural Products into Multiple Trypanosoma brucei Drug Targets. Molecules 2009, 14, 1513-1536
  10. Ogungbe IV and Setzer WN. Cruzain inhibition by terpenoids: A Molecular docking analysis. Nat. Prod. Comm. 2008, 3, 865-868.